Atomic Absorption Spectroscopic Analysis of Heavy Metals in Cancerous Breast Tissues Among Women in Jos, Nigeria

Opeyemi Peter Idowu; Oketayo Oyebamiji Oyedele; Oluwatimilehin Joshua Oluwadare; Wilfred Nwabueze Igboama; Olaniyan Suaib Dolapo; Lawan Ezekiel; Catherine Ignatius; Mashor Mbwas Isaac; Audu Ruth Danbaki; Adefemi Frank Olasele; Hamzat Toheeb Tunde; Bamidele Lateef; Akinnubi Rufus Temidayo

doi:doi:10.11648/j.wjph.20240902.18

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| Peer-Reviewed

Atomic Absorption Spectroscopic Analysis of Heavy Metals in Cancerous Breast Tissues Among Women in Jos, Nigeria

Opeyemi Peter Idowu^*

, Oketayo Oyebamiji Oyedele

, Oluwatimilehin Joshua Oluwadare

, Wilfred Nwabueze Igboama

, Olaniyan Suaib Dolapo

, Lawan Ezekiel, Catherine Ignatius

, Mashor Mbwas Isaac

, Audu Ruth Danbaki, Adefemi Frank Olasele

, Hamzat Toheeb Tunde

, Bamidele Lateef

, Akinnubi Rufus Temidayo

Published in World Journal of Public Health (Volume 9, Issue 2)

Received: 4 March 2024 Accepted: 19 March 2024 Published: 24 May 2024

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Abstract

Breast cancer is prevalent in northern Nigerian women most especially Jos, Plateau State owing to anthropogenic activities such as solid earth mineral mining. In this study, Atomic Absorption Spectrometry was used to determine the levels of eight heavy metals (Cd, As, Cr, Cu, Fe, Pb, Ni and Zn) in cancerous and non-cancerous breast tissues of Jos Nigerian Women. The concentration of heavy metals ranged from 1.08 to 29.34 mg/kg, 0.29 to 10.76 mg/kg, 0.35 to 51.93 mg/kg, 5.15 to 62.93 mg/kg, 11.64 to 51.10 mg/kg, 0.42 to 83.16 mg/kg, 2.08 to 43.07 mg/kg and 1.67 to 71.53 mg/kg for Cd, As, Cr, Cu, Fe, Pb, Ni and Zn respectively. Using MATLAB R2016a, significant differences (t_v = 0.0041 – 0.0317) existed between the levels of all the heavy metals in cancerous and non-cancerous breast tissues except Fe. At 0.01 level of significance, positive significant correlation existed between Pb and Fe, Pb and Cu, Pb and Fe, Ni and Fe, Cr and Pb, as well as Ni and Cr (r = 0.583 – 0.998) in cancerous breast tissues. Using ANOVA, significant differences also occurred in the levels of these heavy metals in cancerous breast tissues (p = 1.910510×10^-26). The relatively high levels of the cancer-induced heavy metals (Cd, As, Cr and Pb) compared with control indicated contamination or exposure to heavy metals which could be the major cause of cancer in these female subjects.

Published in	World Journal of Public Health (Volume 9, Issue 2)
DOI	10.11648/j.wjph.20240902.18
Page(s)	186-193
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Atomic Absorption Spectroscopy, Breast Cancer, Heavy Metal Exposure

References

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Cite This Article

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APA Style

Idowu, O. P., Oyedele, O. O., Oluwadare, O. J., Igboama, W. N., Dolapo, O. S., et al. (2024). Atomic Absorption Spectroscopic Analysis of Heavy Metals in Cancerous Breast Tissues Among Women in Jos, Nigeria. World Journal of Public Health, 9(2), 186-193. https://doi.org/10.11648/j.wjph.20240902.18

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ACS Style

Idowu, O. P.; Oyedele, O. O.; Oluwadare, O. J.; Igboama, W. N.; Dolapo, O. S., et al. Atomic Absorption Spectroscopic Analysis of Heavy Metals in Cancerous Breast Tissues Among Women in Jos, Nigeria. World J. Public Health 2024, 9(2), 186-193. doi: 10.11648/j.wjph.20240902.18

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AMA Style

Idowu OP, Oyedele OO, Oluwadare OJ, Igboama WN, Dolapo OS, et al. Atomic Absorption Spectroscopic Analysis of Heavy Metals in Cancerous Breast Tissues Among Women in Jos, Nigeria. World J Public Health. 2024;9(2):186-193. doi: 10.11648/j.wjph.20240902.18

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@article{10.11648/j.wjph.20240902.18,
  author = {Opeyemi Peter Idowu and Oketayo Oyebamiji Oyedele and Oluwatimilehin Joshua Oluwadare and Wilfred Nwabueze Igboama and Olaniyan Suaib Dolapo and Lawan Ezekiel and Catherine Ignatius and Mashor Mbwas Isaac and Audu Ruth Danbaki and Adefemi Frank Olasele and Hamzat Toheeb Tunde and Bamidele Lateef and Akinnubi Rufus Temidayo},
  title = {Atomic Absorption Spectroscopic Analysis of Heavy Metals in Cancerous Breast Tissues Among Women in Jos, Nigeria
},
  journal = {World Journal of Public Health},
  volume = {9},
  number = {2},
  pages = {186-193},
  doi = {10.11648/j.wjph.20240902.18},
  url = {https://doi.org/10.11648/j.wjph.20240902.18},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.wjph.20240902.18},
  abstract = {Breast cancer is prevalent in northern Nigerian women most especially Jos, Plateau State owing to anthropogenic activities such as solid earth mineral mining. In this study, Atomic Absorption Spectrometry was used to determine the levels of eight heavy metals (Cd, As, Cr, Cu, Fe, Pb, Ni and Zn) in cancerous and non-cancerous breast tissues of Jos Nigerian Women. The concentration of heavy metals ranged from 1.08 to 29.34 mg/kg, 0.29 to 10.76 mg/kg, 0.35 to 51.93 mg/kg, 5.15 to 62.93 mg/kg, 11.64 to 51.10 mg/kg, 0.42 to 83.16 mg/kg, 2.08 to 43.07 mg/kg and 1.67 to 71.53 mg/kg for Cd, As, Cr, Cu, Fe, Pb, Ni and Zn respectively. Using MATLAB R2016a, significant differences (tv = 0.0041 – 0.0317) existed between the levels of all the heavy metals in cancerous and non-cancerous breast tissues except Fe. At 0.01 level of significance, positive significant correlation existed between Pb and Fe, Pb and Cu, Pb and Fe, Ni and Fe, Cr and Pb, as well as Ni and Cr (r = 0.583 – 0.998) in cancerous breast tissues. Using ANOVA, significant differences also occurred in the levels of these heavy metals in cancerous breast tissues (p = 1.910510×10-26). The relatively high levels of the cancer-induced heavy metals (Cd, As, Cr and Pb) compared with control indicated contamination or exposure to heavy metals which could be the major cause of cancer in these female subjects.
},
 year = {2024}
}

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TY  - JOUR
T1  - Atomic Absorption Spectroscopic Analysis of Heavy Metals in Cancerous Breast Tissues Among Women in Jos, Nigeria

AU  - Opeyemi Peter Idowu
AU  - Oketayo Oyebamiji Oyedele
AU  - Oluwatimilehin Joshua Oluwadare
AU  - Wilfred Nwabueze Igboama
AU  - Olaniyan Suaib Dolapo
AU  - Lawan Ezekiel
AU  - Catherine Ignatius
AU  - Mashor Mbwas Isaac
AU  - Audu Ruth Danbaki
AU  - Adefemi Frank Olasele
AU  - Hamzat Toheeb Tunde
AU  - Bamidele Lateef
AU  - Akinnubi Rufus Temidayo
Y1  - 2024/05/24
PY  - 2024
N1  - https://doi.org/10.11648/j.wjph.20240902.18
DO  - 10.11648/j.wjph.20240902.18
T2  - World Journal of Public Health
JF  - World Journal of Public Health
JO  - World Journal of Public Health
SP  - 186
EP  - 193
PB  - Science Publishing Group
SN  - 2637-6059
UR  - https://doi.org/10.11648/j.wjph.20240902.18
AB  - Breast cancer is prevalent in northern Nigerian women most especially Jos, Plateau State owing to anthropogenic activities such as solid earth mineral mining. In this study, Atomic Absorption Spectrometry was used to determine the levels of eight heavy metals (Cd, As, Cr, Cu, Fe, Pb, Ni and Zn) in cancerous and non-cancerous breast tissues of Jos Nigerian Women. The concentration of heavy metals ranged from 1.08 to 29.34 mg/kg, 0.29 to 10.76 mg/kg, 0.35 to 51.93 mg/kg, 5.15 to 62.93 mg/kg, 11.64 to 51.10 mg/kg, 0.42 to 83.16 mg/kg, 2.08 to 43.07 mg/kg and 1.67 to 71.53 mg/kg for Cd, As, Cr, Cu, Fe, Pb, Ni and Zn respectively. Using MATLAB R2016a, significant differences (tv = 0.0041 – 0.0317) existed between the levels of all the heavy metals in cancerous and non-cancerous breast tissues except Fe. At 0.01 level of significance, positive significant correlation existed between Pb and Fe, Pb and Cu, Pb and Fe, Ni and Fe, Cr and Pb, as well as Ni and Cr (r = 0.583 – 0.998) in cancerous breast tissues. Using ANOVA, significant differences also occurred in the levels of these heavy metals in cancerous breast tissues (p = 1.910510×10-26). The relatively high levels of the cancer-induced heavy metals (Cd, As, Cr and Pb) compared with control indicated contamination or exposure to heavy metals which could be the major cause of cancer in these female subjects.

VL  - 9
IS  - 2
ER  -

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Author Information

Opeyemi Peter Idowu

Department of Physics, Federal University, Oye-Ekiti, Ekiti State, Nigeria

Contact Email

http://orcid.org/0000-0002-9887-435X
Oketayo Oyebamiji Oyedele

Department of Physics, Federal University, Oye-Ekiti, Ekiti State, Nigeria

http://orcid.org/0000-0001-9015-7041
Oluwatimilehin Joshua Oluwadare

Department of Physics, Federal University, Oye-Ekiti, Ekiti State, Nigeria

http://orcid.org/0000-0003-2835-0013
Wilfred Nwabueze Igboama

Department of Physics, Federal University, Oye-Ekiti, Ekiti State, Nigeria

http://orcid.org/0000-0002-8215-8869
Olaniyan Suaib Dolapo

Department of Physics, Federal University, Oye-Ekiti, Ekiti State, Nigeria

http://orcid.org/0009-0005-9254-5132
Lawan Ezekiel

Department of Physics, Federal University, Oye-Ekiti, Ekiti State, Nigeria
Catherine Ignatius

Department of Nuclear Engineering/Health Physics, Idaho State University, Pocatello, USA

http://orcid.org/0000-0003-1389-5133
Mashor Mbwas Isaac

Department of Morbid Anatomy, Bingham University Teaching Hospital, Jos, Plateau State, Nigeria

http://orcid.org/0000-0002-6917-2412
Audu Ruth Danbaki

Department of Family Medicine, Bingham University Teaching Hospital, Jos, Plateau State, Nigeria
Adefemi Frank Olasele

Department of Physics, University of Ibadan, Ibadan, Oyo State, Nigeria

http://orcid.org/0009-0004-3040-453X
Hamzat Toheeb Tunde

Department of Physics, Federal University of Agriculture, Abeokuta, Ogun State, Nigeria

http://orcid.org/0009-0007-6898-0665
Bamidele Lateef

Department of Science Laboratory Technology, Osun State College of Technology, Esa-Oke, Osun State, Nigeria

http://orcid.org/0000-0001-8007-4293
Akinnubi Rufus Temidayo

Department of Physics, Adeyemi Federal University of Education, Ondo, Ondo State, Nigeria

http://orcid.org/0000-0001-5708-3917

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Plain Text BibTeX RIS

APA Style

Idowu, O. P., Oyedele, O. O., Oluwadare, O. J., Igboama, W. N., Dolapo, O. S., et al. (2024). Atomic Absorption Spectroscopic Analysis of Heavy Metals in Cancerous Breast Tissues Among Women in Jos, Nigeria. World Journal of Public Health, 9(2), 186-193. https://doi.org/10.11648/j.wjph.20240902.18

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ACS Style

Idowu, O. P.; Oyedele, O. O.; Oluwadare, O. J.; Igboama, W. N.; Dolapo, O. S., et al. Atomic Absorption Spectroscopic Analysis of Heavy Metals in Cancerous Breast Tissues Among Women in Jos, Nigeria. World J. Public Health 2024, 9(2), 186-193. doi: 10.11648/j.wjph.20240902.18

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AMA Style

Idowu OP, Oyedele OO, Oluwadare OJ, Igboama WN, Dolapo OS, et al. Atomic Absorption Spectroscopic Analysis of Heavy Metals in Cancerous Breast Tissues Among Women in Jos, Nigeria. World J Public Health. 2024;9(2):186-193. doi: 10.11648/j.wjph.20240902.18

Copy | Download

@article{10.11648/j.wjph.20240902.18,
  author = {Opeyemi Peter Idowu and Oketayo Oyebamiji Oyedele and Oluwatimilehin Joshua Oluwadare and Wilfred Nwabueze Igboama and Olaniyan Suaib Dolapo and Lawan Ezekiel and Catherine Ignatius and Mashor Mbwas Isaac and Audu Ruth Danbaki and Adefemi Frank Olasele and Hamzat Toheeb Tunde and Bamidele Lateef and Akinnubi Rufus Temidayo},
  title = {Atomic Absorption Spectroscopic Analysis of Heavy Metals in Cancerous Breast Tissues Among Women in Jos, Nigeria
},
  journal = {World Journal of Public Health},
  volume = {9},
  number = {2},
  pages = {186-193},
  doi = {10.11648/j.wjph.20240902.18},
  url = {https://doi.org/10.11648/j.wjph.20240902.18},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.wjph.20240902.18},
  abstract = {Breast cancer is prevalent in northern Nigerian women most especially Jos, Plateau State owing to anthropogenic activities such as solid earth mineral mining. In this study, Atomic Absorption Spectrometry was used to determine the levels of eight heavy metals (Cd, As, Cr, Cu, Fe, Pb, Ni and Zn) in cancerous and non-cancerous breast tissues of Jos Nigerian Women. The concentration of heavy metals ranged from 1.08 to 29.34 mg/kg, 0.29 to 10.76 mg/kg, 0.35 to 51.93 mg/kg, 5.15 to 62.93 mg/kg, 11.64 to 51.10 mg/kg, 0.42 to 83.16 mg/kg, 2.08 to 43.07 mg/kg and 1.67 to 71.53 mg/kg for Cd, As, Cr, Cu, Fe, Pb, Ni and Zn respectively. Using MATLAB R2016a, significant differences (tv = 0.0041 – 0.0317) existed between the levels of all the heavy metals in cancerous and non-cancerous breast tissues except Fe. At 0.01 level of significance, positive significant correlation existed between Pb and Fe, Pb and Cu, Pb and Fe, Ni and Fe, Cr and Pb, as well as Ni and Cr (r = 0.583 – 0.998) in cancerous breast tissues. Using ANOVA, significant differences also occurred in the levels of these heavy metals in cancerous breast tissues (p = 1.910510×10-26). The relatively high levels of the cancer-induced heavy metals (Cd, As, Cr and Pb) compared with control indicated contamination or exposure to heavy metals which could be the major cause of cancer in these female subjects.
},
 year = {2024}
}

Copy | Download

TY  - JOUR
T1  - Atomic Absorption Spectroscopic Analysis of Heavy Metals in Cancerous Breast Tissues Among Women in Jos, Nigeria

AU  - Opeyemi Peter Idowu
AU  - Oketayo Oyebamiji Oyedele
AU  - Oluwatimilehin Joshua Oluwadare
AU  - Wilfred Nwabueze Igboama
AU  - Olaniyan Suaib Dolapo
AU  - Lawan Ezekiel
AU  - Catherine Ignatius
AU  - Mashor Mbwas Isaac
AU  - Audu Ruth Danbaki
AU  - Adefemi Frank Olasele
AU  - Hamzat Toheeb Tunde
AU  - Bamidele Lateef
AU  - Akinnubi Rufus Temidayo
Y1  - 2024/05/24
PY  - 2024
N1  - https://doi.org/10.11648/j.wjph.20240902.18
DO  - 10.11648/j.wjph.20240902.18
T2  - World Journal of Public Health
JF  - World Journal of Public Health
JO  - World Journal of Public Health
SP  - 186
EP  - 193
PB  - Science Publishing Group
SN  - 2637-6059
UR  - https://doi.org/10.11648/j.wjph.20240902.18
AB  - Breast cancer is prevalent in northern Nigerian women most especially Jos, Plateau State owing to anthropogenic activities such as solid earth mineral mining. In this study, Atomic Absorption Spectrometry was used to determine the levels of eight heavy metals (Cd, As, Cr, Cu, Fe, Pb, Ni and Zn) in cancerous and non-cancerous breast tissues of Jos Nigerian Women. The concentration of heavy metals ranged from 1.08 to 29.34 mg/kg, 0.29 to 10.76 mg/kg, 0.35 to 51.93 mg/kg, 5.15 to 62.93 mg/kg, 11.64 to 51.10 mg/kg, 0.42 to 83.16 mg/kg, 2.08 to 43.07 mg/kg and 1.67 to 71.53 mg/kg for Cd, As, Cr, Cu, Fe, Pb, Ni and Zn respectively. Using MATLAB R2016a, significant differences (tv = 0.0041 – 0.0317) existed between the levels of all the heavy metals in cancerous and non-cancerous breast tissues except Fe. At 0.01 level of significance, positive significant correlation existed between Pb and Fe, Pb and Cu, Pb and Fe, Ni and Fe, Cr and Pb, as well as Ni and Cr (r = 0.583 – 0.998) in cancerous breast tissues. Using ANOVA, significant differences also occurred in the levels of these heavy metals in cancerous breast tissues (p = 1.910510×10-26). The relatively high levels of the cancer-induced heavy metals (Cd, As, Cr and Pb) compared with control indicated contamination or exposure to heavy metals which could be the major cause of cancer in these female subjects.

VL  - 9
IS  - 2
ER  -

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